should be distinguished from drug allergy drug intolerance.Complications from medication varying severity observed in one third of patients.Of these, less than 10% are caused by a true allergy to the drug ingredients.Most of the adverse reactions caused by other reasons.Are you familiar themes of drug allergy in the human body?
Drug allergy is characterized by specific immunological reaction to certain medications in patients who are sensitive to allergenic components of these medicines.The most frequently occurs on drug allergy drugs lime penicillin series, and antipyretics, sulfonamides, as well as foreign proteins (blood donations, plasma preparations, therapeutic sera, some hormones and enzymes).Once appearing, drug allergy in humans will occur again and again in the re-admission of a particular drug.Some drugs: aspirin, non-steroidal anti-inflammatory agents such as ipubrufen, ketotifen, naproxen, tserebleks and other drugs - may cause adverse reactions, however, these allergic reaction can not be
intolerance of drugs in the human body is of two categories:
Drug idiosyncrasy unexpected and unpredictable consequences, which are not relevant to the expected effect of the drug (eg, anemia after taking sulfa or painkillers), and drug intolerance -unwanted effects after taking small doses, for which no explanation (e.g., occurrence of tinnitus after taking aspirin).
particularly at risk from medication that category of people who often deal with them.Such patients include patients who suffer from serious illnesses that require the use of high doses of many types of drugs;patients who have impaired liver and kidneys (particularly in patients who abuse alcohol);that category, which has disrupted the immune system.
Signs of drug allergy include:
skin rash as red itchy blisters appear anywhere on the skin.If the reaction in the human body caused by topical application of drugs, rash usually occurs at the point of application.Hives and angioedema as red and itchy spots and swelling that can occur anywhere on the body as a systemic allergic reaction to certain substances.In rare cases, there are other skin manifestations;
the internal organs allergic reaction to the medication can affect the lungs, liver, kidneys, gastrointestinal tract, mucous membranes, cause drug fever, low blood pressure and anemia.Very rarely one drug reactions may be severe allergic complications, leading to death - anaphylaxis.The most common drug - causative agents of an allergic reaction are penicillin, sulfonamides, cephalosporins, insulin, and immune serum.
Often diagnosis of complications from the medication - a rash, fever, swelling, sensitivity of the lymph nodes, and so on. E., Causing some difficulties.
certain medications, the culprit in the development of a negative reaction - a difficult task because, as a rule, sick person takes multiple medications.
symptoms diary can greatly help your doctor in proper diagnosis.However, apart from the diary of symptoms it is advisable to keep a diary of medication.In the diary of medication necessary to observe the following information: the name of all the medicines you are taking or have taken early at the present time;for the prevention and treatment of any disease you accept them;efficiency and outcomes;side effects or adverse reactions you experienced during treatment.
There are ways to reduce the risk of adverse reactions from the drugs.One of the most important ways to prevent adverse reactions is to avoid exposure to them.The risk of drug allergy is reduced if used drugs (especially local) is not on any occasion, but only when they are really needed.
Medication effects of adverse reactions to drugs usually includes receiving one or more antihistamines and, if necessary, a short course of treatment with oral systemic corticosteroids (especially in inflammation of the joints).Treatment of life-threatening complications (anaphylactic reaction) requires immediate use of epinephrine, oxygen, corticosteroids and antihistamines.If you have a non-immunological negative reaction to medication, which, despite this, the doctor considers it necessary to recommend that the need to spend a short prophylactic course with oral corticosteroids and antihistamines.
In case of allergy to penicillin should be avoided and other antibiotics of penicillin (ampicillin, amoxicillin) and antibiotic of cephalosporin as in patients allergic to penicillin can form cross-allergies.